Screening pedigreed data sets for evidence of major genes
What is a major gene?
PPT Slide
Example: the Booroola gene
Detection of major genes
Detection: simple statistical tests
Detection: complex segregation analysis
Simple segregation analysis
Model for phenotype with major gene
Findgene method
Findgene uncorrected phenotypes
Findgene corrected phenotypes
Gibbs sampling chain for a major gene effect
Other useful major genes
Limitations of segregation analysis
Advantages of segregation analysis
Email: bkinghor@metz.une.edu.au
Home Page: http://metz.une.edu.au/~bkinghor/